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A variety of studies have measured and investigated the causes for differences between individuals in the sense of fine touch. One well-studied area is passive tactile spatial acuity, the ability to resolve the fine spatial details of an object pressed against the stationary skin. A variety of methods have been used to measure passive tactile spatial acuity, perhaps the most rigorous being the grating orientation task. In this task subjects identify the orientation of a grooved surface presented in two different orientations, which can be applied manually or with automated equipment. Many studies have shown a decline in passive tactile spatial acuity with age; the reasons for this decline are unknown, but may include loss of tactile receptors during normal aging. Remarkably, index finger passive tactile spatial acuity is better among adults with smaller index fingertips; this effect of finger size has been shown to underlie the better passive tactile spatial acuity of women, on average, compared to men. The density of tactile corpuscles, a type of mechanoreceptor that detects low-frequency vibrations, is greater in smaller fingers; the same may hold for Merkel cells, which detect the static indentations important for fine spatial acuity. Among children of the same age, those with smaller fingers also tend to have better tactile acuity. Many studies have shown that passive tactile spatial acuity is enhanced among blind individuals compared to sighted individuals of the same age, possibly because of cross modal plasticity in the cerebral cortex of blind individuals. Perhaps also due to cortical plasticity, individuals who have been blind since birth reportedly consolidate tactile information more rapidly than sighted people.

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