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The theory proposed considered to be the most likely evolution of running is of early humans' developing as endurance runners from the practice of persistence hunting of animals, the activity of following and chasing until a prey is too exhausted to flee, succumbing to "chase myopathy" (Sears 2001), and that human features such as the nuchal ligament, abundant sweat glands, the Achilles tendons, big knee joints and muscular glutei maximi, were changes caused by this type of activity (Bramble & Lieberman 2004, et al. ). The theory as first proposed used comparative physiological evidence and the natural habits of animals when running, indicating the likelihood of this activity as a successful hunting method. Further evidence from observation of modern-day hunting practice also indicated this likelihood (Carrier et al. 1984). According to Sears (p.  12) scientific investigation (Walker & Leakey 1993) of the Nariokotome Skeleton provided further evidence for the Carrier theory.

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